Science

Hospitals are Hotspots for Antibiotic-resistant Germs

Thanks again to the Koslicki Lab at Penn State for supporting this episode. Their lab focuses on computational biology, including the analysis of metagenomic data. If you enjoyed this video, check out some of their papers: https://koslickilab.github.io/Koslicki-lab-PSU/

While antibiotics have saved millions of lives, misusing them can speed up how fast bacteria evolve to resist them. And it turns out that one of the biggest hotspots for these antibiotic-resistant bacteria…is hospitals.

Hosted by: Hank Green

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Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351745/
https://www.sciencedirect.com/science/article/pii/S2215017X21000205
https://www.genome.gov/genetics-glossary/Metagenomics
https://www.nature.com/articles/s41591-020-0894-4
https://www.researchgate.net/publication/354110983_Metagenomic_Analysis_of_Antibiotic_Resistance_Genes_in_Untreated_Wastewater_From_Three_Different_Hospitals
https://www.frontiersin.org/articles/10.3389/fmicb.2017.02200/full
https://www.sciencedirect.com/science/article/abs/pii/S2213716516300261
https://asm.org/Articles/2019/November/Metagenomic-Next-Generation-Sequencing-How-Does-It
https://health.adelaide.edu.au/florey120anniversary/one-discovery-that-changed-the-world
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378521/
https://www.cdc.gov/antibiotic-use/q-a.html
https://www.frontiersin.org/articles/10.3389/fgene.2020.575592/full
https://www3.epa.gov/npdes/pubs/centralized_brochure.pdf
https://www.frontiersin.org/articles/10.3389/fmicb.2019.00338/full

Images:
Antibiotics
https://www.istockphoto.com/photo/different-samples-with-kinds-of-bacterias-living-at-common-household-items-tothbrush-gm1153660896-313409321
https://commons.wikimedia.org/wiki/File:Environmental_shotgun_sequencing.png
https://www.istockphoto.com/photo/recovery-room-with-bed-and-comfortable-medical-interior-of-empty-hospital-room-gm1271748163-374232068
https://www.istockphoto.com/photo/gowanus-canal-brooklyn-ny-gm469514832-61645610
https://www.istockphoto.com/photo/the-human-microbiome-genetic-material-of-all-the-microbes%C2%A0that-live-on-and-inside-gm1279892500-378359062
https://www.istockphoto.com/photo/pediatrician-talks-with-patients-mother-gm1293681788-387996282
https://www.istockphoto.com/photo/nasal-and-oral-cavity-anatomical-model-for-medical-study-on-doctors-table-ent-doctor-gm1298086611-391024785
https://www.istockphoto.com/photo/clarifier-at-wastewater-treatment-plant-aerial-view-gm1283959509-381239317
https://www.istockphoto.com/photo/empty-modern-hospital-corridor-gm1294129593-388236812
https://www.istockphoto.com/photo/abstract-squiggle-pattern-in-molten-milk-chocolate-gm172316284-4238934
https://www.istockphoto.com/photo/red-chairs-gm539971320-96333967
https://www.istockphoto.com/photo/i-have-really-bad-chest-pain-doctor-gm1286713035-383135197
https://www.istockphoto.com/photo/moraxella-catarrhalis-bacteria-illustration-gram-negative-aerobic-bacterium-gm1314473963-402678064

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